WP4 - (Sub-)cellular targets and mechanisms

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Work package 4 aims at discovering the mechanisms of actions of flavanols (a group of phytonutrients) in human vascular cells.
Outcomes
  • The main food sources of flavanols among the EU population are tea, pome fruit (apples, pears, etc.), berries and small fruit, cocoa products, and stone fruit
  • There are no significant differences in the absorption of overall flavanols between young and elderly men, but there are significant differences in the types of resulting metabolites found in the body due to differences in metabolism
  • Dietary cocoa flavanols improved cardiovascular function in healthy young and elderly subjects
Innovation
  • Creation of food database and expansion of existing databases to assess flavanol intake
Work package 4 aims at discovering the mechanisms of actions of flavanols (a group of phytonutrients) in human vascular cells.
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